Blar i forfatter "Fuskevåg, Ole-Martin"

Viser treff 1-10 av 10

    • Autocrine Prostaglandin E-2 Signaling Promotes Tumor Cell Survival and Proliferation in Childhood Neuroblastoma 

      Rasmuson, Agnes; Kock, Anna; Fuskevåg, Ole-Martin; Kruspig, Björn; Simon-Santamaria, Jaione; Gogvadze, Vladimir; Johnsen, John Inge; Kogner, Per; Sveinbjørnsson, Baldur (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Prostaglandin E2 (PGE2) is an important mediator in tumor-promoting inflammation. High expression of cyclooxygenase-2 (COX-2) has been detected in the embryonic childhood tumor neuroblastoma, and treatment with COX inhibitors significantly reduces tumor growth. Here, we have investigated the significance of a high COX-2 expression in neuroblastoma by analysis of PGE2 production, the expression pattern ...

    • Effects of Vitamin D binding protein phenotypes and Vitamin D supplementation on serum total 25(OH)D and directly measured free 25(OH)D 

      Sollid, Stina Therese; Strand Hutchinson, Moira; Berg, Vivian; Fuskevåg, Ole-Martin; Figenschau, Yngve Anton; Thorsby, Per Medbøe; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-05)
      Objective:<br>To determine the relationship between serum total 25-hydroxyvitamin D (25(OH)D), directly measured free 25(OH)D and calculated free 25(OH)D with regard to vitamin D-binding protein (DBP) phenotypes, sex, BMI, age and season, and their interrelationship to vitamin D supplementation.<br>Design, patients and interventions:<br>A randomized controlled trial with 20 000 IU of vitamin D3 per ...

    • Estimated GFR is biased by non-traditional cardiovascular risk factors 

      Melsom, Toralf; Fuskevåg, Ole-Martin; Mathisen, Ulla Dorte; Strand, Harald; Schei, Jørgen; Jenssen, Trond Geir; Solbu, Marit Dahl; Eriksen, Bjørn Odvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-23)
      Background: Estimated glomerular filtration rate (eGFR) based on either cystatin C or creatinine perform similarly in estimating measured GFR, but associate differently with cardiovascular disease (CVD) and mortality. This could be due to confounding by non-GFRrelated traits associated with cystatin C and creatinine levels. We investigated non-GFRrelated associations between eGFR and two types ...

    • Gradually decreasing daylength after smoltification induced by “winter signal“ reduced sexual maturation in male Atlantic salmon 

      Skjold, Vetle; Rørvik, Kjell-Arne; Sveen, Lene; Burgerhout, Erik; Mota, Vasco C.; Weihe, Runi; Ytrestøyl, Trine; Bou, Marta; Jacobsen, Hans Jakup; Allaoui, Giovanni; Fuskevåg, Ole-Martin; Dessen, Jens-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-16)
      Introduction: Maturation in seawater-adapted (smoltified) male Atlantic salmon is undesirable yet frequently reported in fish weighing up to 1 kg reared under intensive conditions in land-based facilities. Although the photoperiod regulates both smoltification and maturation, the optimal post-smoltification regimen for the prevention of maturation is unclear.<p> <p>Methods: In this study, ...

    • The impact of partial hepatectomy on oxidative state in the liver remnant - An in vivo swine model 

      Florholmen-Kjær, Åse; Goll, Rasmus; Fuskevåg, Ole-Martin; Nygård, Ingvild; Paulssen, Ruth H; Revhaug, Arthur; Mortensen, Kim Erlend (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-24)
      Background Previous studies on oxidative state after partial hepatectomy (PHx) report conflicting data on levels of glutathione (GSH) and are mainly presented in rodent models by methodology less sensitive than the present technologies. The current swine model presents GSH levels and the following genetic response post-PHx, utilizing an analytical platform more sensitive and precise than earlier ...

    • Maternal serum concentrations of per- and polyfluoroalkyl substances and their predictors in years with reduced production and use 

      Berg, Vivian; Nøst, Therese Haugdahl; Huber, Sandra; Rylander, Charlotta; Hansen, Solrunn; Veyhe, Anna Sofia; Fuskevåg, Ole-Martin; Odland, Jon Øyvind; Sandanger, Torkjel Manning (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Persistent Organic Pollutants in Norwegian Men from 1979 to 2007: Intraindividual Changes, Age–Period–Cohort Effects, and Model Predictions 

      Nøst, Therese Haugdahl; Breivik, Knut; Fuskevåg, Ole-Martin; Nieboer, Evert; Odland, Jon Øyvind; Sandanger, Torkjel Manning (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Longitudinal monitoring studies of persistent organic pollutants (POPs) in human populations are important to better understand changes with time and age, and for future predictions. Objectives: We sought to describe serum POP time trends on an individual level, investigate age–period–cohort effects, and compare predicted polychlorinated biphenyl (PCB) concentrations to measured values. ...

    • The role of OAT2 (SLC22A7) in the cyclic nucleotide biokinetics of human erythrocytes 

      Sager, Georg; Smaglyukova, Natalia; Fuskevåg, Ole-Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-15)

    • Sodium nitroprusside inhibits HEK293 cell growth by cGMP-dependent and independent mechanisms 

      Sager, Georg; Sundkvist, Elisabeth; Jæger, Ragnhild; Lyså, Roy Andre; Fuskevåg, Ole-Martin; Fuskevåg, Ole-Martin (Journal article; Tidsskriftartikkel, 2014)

    • Urinary Markers of Oxidative Stress Are Associated With Albuminuria But Not GFR Decline 

      Schei, Jørgen; Fuskevåg, Ole-Martin; Stefansson, Vidar Tor Nyborg; Solbu, Marit Dahl; Jenssen, Trond Geir; Eriksen, Bjørn Odvar; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-07)
      <p><i>Introduction</i>: Markers of oxidative stress increase with age and are prevalent with chronic kidney disease. However, the role of oxidative stress markers as predictors for kidney function decline in the general population is unclear.</p> <p><i>Methods</i>: We investigated whether a baseline urinary excretion of oxidative DNA damage (8-oxo-7,8-dihydro-2′-deoxyguanosine [8-oxodG]) and ...